Mc. Pietrogrande et al., HRGC SEPARATION PERFORMANCE EVALUATION BY A SIMPLIFIED FOURIER-ANALYSIS APPROACH, HRC. Journal of high resolution chromatography, 19(6), 1996, pp. 327-332
A simple procedure is presented for determining separation performance
of HRGC analysis of multicomponent mixtures. The procedure is based o
n the computation of Autocovariance Function (EACVF) from the digitize
d experimental chromatogram Graphic inspection of the EACVF plot permi
ts easy computation of the width value of the single component peak, s
igma; from the EACVF value at t = 0 the number of component in the mix
ture, m, can be simply derived, From these two basic quantities ail th
e other chromatographic performance attributes can be calculated, The
consistency of the procedure is tested for different chromatograms and
compared with the more complex EACVF fitting method, Several features
of the multicomponent chromatogram overloading effects included, are
directly detected.