Anesthesia personnel are at risk for occupationally acquired blood-bor
ne infections from human immunodeficiency virus, hepatitis viruses, an
d others after percutaneous exposures to infected blood or body fluids
. The risk is greater after an infected, blood-contaminated, percutane
ous injury, especially from a hollow-bore blood-filled needle, than fr
om other types of exposures. Few data are available on the specific oc
cupational hazards to anesthesia personnel from needles and other shar
p devices. Fifty-eight percutaneous injuries (PIs) from anesthesia per
sonnel in nine hospitals were analyzed. Thirty-nine of 58 PIs were fro
m contaminated devices (all needles), and 19 were from uncontaminated
devices or of unknown contamination status. Forty-three percent of con
taminated percutaneous injuries (CPI) were classified as moderate (som
e bleeding) or severe (deep injury with profuse bleeding), and most we
re to health-care workers' hands. Fifty-nine percent of CPI were poten
tially preventable. Eighty-seven percent of CPI were from hollow-bore
needles, and 68% of these were potentially preventable. The largest ca
tegories of devices causing CPI were needle on syringe, intravenous (I
V) or arterial catheter needle-stylet, suture needle, and standard hol
low-bore needle for secondary IV infusion. Most CPI occurred between s
teps of a multistep procedure (8%), were recapping related (13%), or o
ccurred at other times after use (41%). No CPI were reported from use
of needlestick-prevention safety devices. The devices and mechanisms o
f injury identified in this study provide specific data that may lead
to prevention strategies to reduce the risk of PI.