ANTIMICROBIALS PRESCRIBED FOR OTITIS-MEDIA IN A PEDIATRIC MEDICAID POPULATION

Citation
Ll. White et al., ANTIMICROBIALS PRESCRIBED FOR OTITIS-MEDIA IN A PEDIATRIC MEDICAID POPULATION, American journal of health-system pharmacy, 53(24), 1996, pp. 2963-2969
Citations number
20
Categorie Soggetti
Pharmacology & Pharmacy
ISSN journal
10792082
Volume
53
Issue
24
Year of publication
1996
Pages
2963 - 2969
Database
ISI
SICI code
1079-2082(1996)53:24<2963:APFOIA>2.0.ZU;2-N
Abstract
Antimicrobial prescribing patterns for Tennessee Medicaid children hav ing their first case of otitis media (OM) in at least nine months were studied. Tennessee Medicaid claims data for patients under 11 years w hose first documented OM diagnosis in 1993 occurred in the fourth quar ter and who had had an antimicrobial claim filed within two days of di agnosis were studied to determine antimicrobial prescribing patterns. Of 7357 children meeting the study criteria, 70% were less than three years of age, 65% were Caucasian, and 60% had a rural address. Twenty antimicrobials were prescribed. Amoxicillin was prescribed most freque ntly (53% of the time), followed by cefaclor; all first-line therapies (amoxicillin, ampicillin, erythromycin-sulfisoxazole, and trimethopri m-sulfamethoxazole) accounted for 64% of the prescriptions, but only o ne fourth of the costs. The highest use of first-line therapy was asso ciated with children under three years of age; children without prior antimicrobial therapy, recent upper respiratory infection (URI), or re cent sinusitis; children seen by emergency department physicians; and children seen by urban physicians. Tennessee Medicaid would have saved $68,250 if first-line therapy had been used for all children having t heir first occurrence of OM in the fourth quarter alone. The savings t o the state were estimated at $300,000 or more in 1993 had first-line therapy been used for most first occurrences of OM in all four quarter s plus even a small percentage of the estimated 30,000 remaining repea t OM cases. Amoxicillin was prescribed 53% of the time, and all first- line therapies 64% of the time, for children with their first case of OM in at least nine months. In children without recent antimicrobial t herapy, URI, or sinusitis, first-line therapy was still used only 72% of the time.