This study examined differences in the spontaneous electroencephalogra
phic (EEG) signal in terms of music training and gender. Coherence est
imates obtained by spectral analysis provided an efficacious method to
study these differences. In the first study, differences in the spont
aneous EEG between subjects with and without music training were obser
ved. Subjects with music training exhibited significantly higher coher
ence values both within and between cerebral hemispheres when compared
with subjects without music training. The most striking differences w
ere observed in the two lowest (delta and theta) and two highest (beta
1 and beta 2) bands, with differences in the temporoparietal regions
of both hemispheres being most prominent. The findings are discussed i
n terms of specialized organization of brain activity that influences
cortical connectivity. Using the same method, differences in spontaneo
us EEG were also found between male and female subjects. Females tende
d to have significantly higher interhemispheric coherence values when
compared with males. Both findings are also supported by recently disc
overed anatomic differences.