B. Legoux et al., METASTATIC MELANOMA TO THE HEART - A CASE -REPORT WITH CARDIAC TAMPONNADE, Annales de dermatologie et de venereologie, 123(6-7), 1996, pp. 393-394
Introduction. Melanoma is the most frequent cause of neoplastic metast
asis to the heart. The diagnosis is however usually made after the pat
ient's death as clinical signs are discrete, non-specific or masked by
other visceral metastases. Case report. A 50-year-old man who was giv
en chemotherapy for metastatic melanoma limited to the mediastinal lym
ph nodes suddenly developed acute dyspnea due to cardiac tamponnade. P
uncture biopsy of the pericardium revealed melanoma cells and nodular
infiltration of the pericardium. A pleuro-pericardial window gave func
tional relief. The patient died 5 months later due to a recurrent epis
ode of cardiac tamponnade. Discussion. The diagnosis of metastasis to
the heart of a malignant melanoma may be suspected in patients develop
ing heart failure, rhythm or conduction disorders or pericardial effus
ion. The diagnosis can usually be confirmed with transthoracic sonogra
phy. Endocavitary or transmural tumors may require transesophageal ech
ography or magnetic resonance imaging before surgery to determine exte
nsion and myocardial infiltration. Despite the severe prognosis, in ca
se of immediate life-threatening emergencies or isolated cardiac metas
tases, a surgical treatment may be considered.