HYPERIMMUNOGLOBULINEMIA-D - AN ETIOLOGY F OR FAMILIAL URTICARIA IN CHILDHOOD

Objective. Recall the main elements suggesting the diagnosis of hyperi mmunoglobulinemia D based on a family case of chronic urticaria. Case report. A boy and his mother presented the same signs of urticaria, fe ver and joint pain. Laboratory results showed an inflammatory syndrome in both. In the child, the first manifestations occurred during the a ge of one year. Hyperimmunoglobulinemia D was confirmed by persistentl y high serum levels. Conclusion. The diagnosis of hyperimmunoglobuline mia D can be entertained in a child in a family with chronic urticaria . Fever, joint pain, digestive disorders and enlarged lymph nodes are suggestive and the diagnosis is confirmed by a clear elevation of seru m IgD.