OBTECTIVE: To compare the effects of laparoscopic and open surgical pr
ocedures on postoperative strength and respiratory mechanics. DESIGN:
Prospective cohort study. SETTING: Adult university hospital. PARTICIP
ANTS: Fifty-one women aged 21 to 62 years scheduled to undergo electiv
e cholecystectomy or hysterectomy (or related procedures), othwrwise i
n good health. INTERVENTION: Open or laparoscopic cholecystectomy or h
ysterectomy (or related procedures). MAIN OUTCOME MEASURES: Maximum vo
luntary handgrip strength (HGS), forced vital capacity (VC), forced es
piratory volume in 1 second (FEV(1)), and maximal inspiratory pressure
(MIP) were each measured preoperatively and on the first postoperativ
e morning. A visual analogue pain scale score was evaluated in relatio
n to performance of the postoperative strength and respiratory measure
ments. RESULTS: VC, FEV, and MIP, but not HGS, were decreased after su
rgery. Postoperative VC, FEV, and MIP were lower after open procedures
than after laparoscopic procedures and after cholecystectomy than aft
er hysterectomy (all p < 0.001). Pain scores were lower after laparosc
opic than after open procedures (p < 0.005) and could account in part
for differences in postoperative respiratory mechanics. CONCLUSIONS: C
holecystectomy and hysterectomy do not result in generalized muscle we
akness, unlike more major abdominal procedures. Postoperative alterati
ons in respiratory mechanics are related to the site of the surgery, t
he use of an open versus a laparoscopic approach and postoperative pai
n.