Hypersensitivity reactions induced by tetracyclines are uncommon. A 41
-year-old man developed a hypersensitivity pneumonitis following treat
ment with minocycline. The disease responded to withdrawal of the drug
. T-lymphocytes may play a central role in the pathogenesis of this pn
eumonitis. This observation shows that minocycline, despite its mild t
oxicity profile, can give rise to serious adverse effects.