QUANTITATIVE APPROACH OF ANTIINFECTIOUS DRUGS USED IN LATE-STAGE AIDSPATIENTS IN A FRENCH HOSPITAL

To describe the amount anal costs of anti-infectious drugs used in lat e stage AIDS' patients in a french hospital we conducted a retrospecti ve analysis of drugs used in those patients, during the last three mon ths before death, in the Department of Infectious Diseases in Toulouse , France, The follow up of the patients was at least of 1 year in the Dpt, The study population (47 patients, 209 hospitalizations) was comp arable with the local population of AIDS' cases in regard to age, sex, and risk factors, The mean survival after diagnosis of aids was 2 yea rs, The mean duration of hospitalization was 13,5 days, for an average of 4,45 hospitalizations per patient in three months, More or less 5 differents drugs were used during one hospitalization, of wich 65 % we re anti-infectious. Anti-parasitic drugs accounted for 35 % (antimycot ic 13 %, anti-toxoplasmic 13 %, anti-pneumocystis 8 %) - Antibiotics f or 18 % (Broad spectrum 10,5 %, anti-MAC 7 %, anti-tuberculosis 1 %)- Anti-viral drugs for 12 % (anti-CMV 5,5 %, anti-HSV 4 %, anti-HIV 3 %) , This quantitative approach takes into account the load of anti-infec tious drugs and their respective costs in the health care expenditure at the late stage of AIDS.