REACTIONS OF TUMOR-CELL CULTURES ON THE I NFLUENCE OF LOW-FREQUENCY LOW-INTENSITY ELECTROMAGNETIC-FIELDS

The influence of extremely-low-frequency electromagnetic fields (LFLI EMF) on the cells of human histiocytic lymphoma U-937 and melanoma B16 was investigated. The EMF-treatment of lymphoma cells resulted in the significant changes of the rate of DNA synthesis and growth of cell p opulation. After the influence, melanoma cells showed the inhibition a nd stimulation of aggregability. The tumorogenicity and metastatic act ivity of the EMF-treated melanoma B16 cells were significantly suppres sed after the transplantation of the cells into animals. Since the obs erved effects show nonlinear dependence on the frequency-amplitude par ameters of the applied EMFs, the occurrence of bioresonance response o f the cells to the influence of EMF is supposed. It is assumed that th e applied EMFs were biological in nature and emitted by the malignant cells.