BONE-SCINTIGRAPHY IN HUNGRY BONE SYNDROME FOLLOWING PARATHYROIDECTOMY

A 59-yr-old man with chronic renal failure was admitted for evaluation of generalized skeletal pain and frontal bone mass, which was lyric o n radiography. Bone scintigraphy demonstrated several fool of moderate ly increased uptake, without involvement of the skull mass. Radiograph s of these lesions were compatible with brown tumors. Serum parathormo ne level was elevated and CT demonstrated a lower right cervical mass, consistent with parathyroid tumor. Following the removal of the mass and decrease in parathormone levels, the patient suffered from a prolo nged period of hypocalcemia and his bone pain worsened. Repeat bone sc intigraphy showed an increase in the number and intensity of the areas of focal uptake, consistent with hungry bone syndrome. This flare-up phenomenon is due to an increase in bone metabolism and is an uncommon finding following parathyroidectomy for primary hyperparathyroidism.