H. Haller et al., TRANSVAGINAL SONOGRAPHY AND HYSTEROSCOPY IN WOMEN WITH POSTMENOPAUSALBLEEDING, International journal of gynaecology and obstetrics, 54(2), 1996, pp. 155-159
Objective: To make a prospective comparison between endometrial thickn
ess determined by transvaginal sonography (TVS) and hysteroscopic find
ings in women with postmenopausal bleeding with histologic findings ob
tained by dilatation and curettage (D&C). Methods: Eighty-one patients
who had not received hormonal replacement therapy were scanned by tra
nsvaginal probe, and double-layer endometrial thickness was measured 1
day before hysteroscopy and D&C. Results: The histologic diagnosis wa
s atrophy in 12 cases, irregular proliferative changes in 21, endometr
ial polyps in 16, hyperplasia in 16 and endometrial carcinoma in 16. T
VS detected 46 of 48 pathologic conditions, including all cases of end
ometrial carcinoma if the endometrial thickness (both layers) was grea
ter than or equal to 5 mm (sensitivity 95.8%, specificity 45.5%). Hyst
eroscopy also detected the endometrial pathology in 46 of 48 cases but
with a higher specificity (sensitivity 95.3%, specificity 93.9%). Con
clusion: TVS and hysteroscopy are complementary diagnostic methods and
could be accurately used to discriminate between normal and pathologi
c conditions in patients with postmenopausal bleeding.