Since mid-1989, 37 cases of oleander poisoning in livestock have been
diagnosed at the California Veterinary Diagnostic Laboratory System. T
he most frequent source for oleander exposure was plant clippings. Sud
den death was the most common presenting complaint. Other signs report
ed included diarrhea, pulmonary edema, tachycardia, cardiac arrhythmia
s, colic, and lethargy. In the past, a presumptive diagnosis of oleand
er poisoning could be based only on matching clinical signs with evide
nce of consumption of oleander. A new 2 dimensional Thin-layer chromat
ography analysis of ingesta for oleandrin and an awareness of lesions
in heart muscle have greatly improved the ability to diagnose oleander
toxicosis.