APO-E GENOTYPE AND VERBAL DEFICITS IN ALZHEIMERS-DISEASE

Authors
RASMUSSON DX DALFORNO G BRANDT J WARREN AC TRONCOSO J LYKETSOS C
Citation
Dx. Rasmusson et al., APO-E GENOTYPE AND VERBAL DEFICITS IN ALZHEIMERS-DISEASE, The Journal of neuropsychiatry and clinical neurosciences, 8(3), 1996, pp. 335-337
Citations number
13
Categorie Soggetti
Neurosciences,"Clinical Neurology",Psychiatry
Journal title
The Journal of neuropsychiatry and clinical neurosciences → ACNP
ISSN journal
08950172
Volume
8
Issue
3
Year of publication
1996
Pages
335 - 337
Database
ISI
SICI code
0895-0172(1996)8:3<335:AGAVDI>2.0.ZU;2-6
Abstract
Apo-E genotype was not significantly related to cognitive performance in 157 Alzheimer's disease patients. However, patients homozygous for the epsilon 4 allele appeared most impaired an global cognition but le ast impaired on language measures. Further study with larger samples m ay reveal that Apo-E genotype accounts for some of the variability in cognitive deficits observed in Alzheimer's disease.