Objectives: To describe a patient with a spontaneous spinal epidural h
ematoma associated wth cocaine use and to present issues related to pa
thogenesis and management of this potential complication. Design: Case
report. Setting: Municipal hospital. Case: A spontaneous spinal epidu
ral hematoma developed at the thoracic level in a 62-year-old man in a
ssociation with cocaine use. Clinical, laboratory, and radiologic data
are presented. Main Outcome and Results: The patient was treated medi
cally with intravenous and oral dexamethasone sodium phosphate. His ne
urologic status gradually improved during a 12-day hospitalization. Co
nclusion: Cocaine use should be considered in the evaluation of sponta
neous spinal epidural hemorrhage.