SHORT-TERM GROWTH-HORMONE THERAPY INCREASES SERUM-LIPOPROTEIN (A) LEVELS IN NORMAL SHORT CHILDREN WITHOUT GROWTH-HORMONE DEFICIENCY

Authors
HERSHKOVITZ E LEIBERMAN E LIMONY Y SHANY S PHILLIP M
Citation
E. Hershkovitz et al., SHORT-TERM GROWTH-HORMONE THERAPY INCREASES SERUM-LIPOPROTEIN (A) LEVELS IN NORMAL SHORT CHILDREN WITHOUT GROWTH-HORMONE DEFICIENCY, Hormone research, 46(1), 1996, pp. 38-40
Citations number
9
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Hormone research → ACNP
ISSN journal
03010163
Volume
46
Issue
1
Year of publication
1996
Pages
38 - 40
Database
ISI
SICI code
0301-0163(1996)46:1<38:SGTIS(>2.0.ZU;2-T
Abstract
We investigated the short-term effect of GH (0.1 IU/kg/day) on serum l ipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 pears. GH increased serum Lp(a) concentrations in all the children studied, An i ncrease to 107+/-5, 161.6+/-14.7 and 152.5+/-8.5% (mean+/-SE) of basel ine levels was observed after 2 (p=NS), 6 (p <0.01) and 12 weeks (p <0 .05), respectively. Our results suggest that GH therapy may pose a sig nificant influence on Lp(a) serum levels in non-GH-deficient short chi ldren.