INVERSE ELECTRON DEMAND DIELS-ALDER REACTIONS OF INDOLE .5. REACTIONSOF 3-SUBSTITUTED INDOLES WITH HETEROAROMATIC AZADIENES

Authors
BENSON SC LEE L SNYDER JK
Citation
Sc. Benson et al., INVERSE ELECTRON DEMAND DIELS-ALDER REACTIONS OF INDOLE .5. REACTIONSOF 3-SUBSTITUTED INDOLES WITH HETEROAROMATIC AZADIENES, Tetrahedron letters, 37(29), 1996, pp. 5061-5064
Citations number
37
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
29
Year of publication
1996
Pages
5061 - 5064
Database
ISI
SICI code
0040-4039(1996)37:29<5061:IEDDRO>2.0.ZU;2-H
Abstract
The inverse electron demand Diels-Alder reactions of 3-substituted ind oles with 1,2,4-triazines and 1,2,4,5-tetrazines proceeded in excellen t yields both inter- and intramolecularly. The cycloaddition of trypto phan with a tethered 1,2,4-triazine produced a diastereomerically pure cycloadduct. Copyright (C) 1996 Elsevier Science Ltd