ASYMMETRIC ALLYLATION OF ALDEHYDES CATALYZED BY SUBSTOICHIOMETRIC AMOUNTS OF CHIRAL PHOSPHORAMIDES

Authors
ISEKI K KUROKI Y TAKAHASHI M KOBAYASHI Y
Citation
K. Iseki et al., ASYMMETRIC ALLYLATION OF ALDEHYDES CATALYZED BY SUBSTOICHIOMETRIC AMOUNTS OF CHIRAL PHOSPHORAMIDES, Tetrahedron letters, 37(29), 1996, pp. 5149-5150
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
29
Year of publication
1996
Pages
5149 - 5150
Database
ISI
SICI code
0040-4039(1996)37:29<5149:AAOACB>2.0.ZU;2-C
Abstract
The asymmetric allylation and crotylation of aromatic aldehydes with a llylic trichlorosilanes catalyzed by substoichiometric quantities of c hiral phosphoramides were carried our with good enantiomeric excess (u p to 88% ee). Phosphoramides 3 and 4, prepared from (S)-proline, gave chiral homoallylic alcohols 6 and their enantiomers 7, respectively, w ith similar levels of enantioselectivity. Copyright (C) 1996 Elsevier Science Ltd