RUTHENIUM TETROXIDE OXIDATION OF 3-BETA-ACETOXY-28-HYDROXY-18-LUPENE TO TRICYCLIC PRODUCTS

Authors
DENISENKO MV POKHILO ND ODINOKOVA LE DENISENKO VA UVAROVA NI
Citation
Mv. Denisenko et al., RUTHENIUM TETROXIDE OXIDATION OF 3-BETA-ACETOXY-28-HYDROXY-18-LUPENE TO TRICYCLIC PRODUCTS, Tetrahedron letters, 37(29), 1996, pp. 5187-5190
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
29
Year of publication
1996
Pages
5187 - 5190
Database
ISI
SICI code
0040-4039(1996)37:29<5187:RTOO3T>2.0.ZU;2-Q
Abstract
By gradual addition 3 beta-acetoxy-28-hydroxy-18-lupene with stirring at similar to 50 degrees C EtOAc-H2O biphase system, containing F3CCOO H and RuO4, regenerated in situ from RuO2 . xH(2)O and NaIO4, satisfac tory yields of 3 -28-nor-17,18;18,19-disecolupaan-17,19-dion-18-oic ac id and 3 -19,20,21,22,28,29,30-heptanor-17,18-secolupan-17, 18-dioic a cid were obtained. Copyright (C) 1996 Elsevier Science Ltd