DNA-PROTEIN INTERACTIONS - 2 STEPS TO BINDING REPLICATION ORIGINS

Authors
DEAN FB ODONNELL M
Citation
Fb. Dean et M. Odonnell, DNA-PROTEIN INTERACTIONS - 2 STEPS TO BINDING REPLICATION ORIGINS, Current biology, 6(8), 1996, pp. 931-934
Citations number
14
Categorie Soggetti
Biology,Biology
Journal title
Current biology → ACNP
ISSN journal
09609822
Volume
6
Issue
8
Year of publication
1996
Pages
931 - 934
Database
ISI
SICI code
0960-9822(1996)6:8<931:DI-2ST>2.0.ZU;2-U
Abstract
Recent structural studies of the Epstein-Barr virus EBNA1 protein boun d to DNA suggest that it binds to DNA replication origins in a two-ste p process; the first step involves recognition of the correct sequence and the second initiates structural changes in the DNA.