GENOME STABILITY - KEEPING THE CENTROSOME CYCLE ON TRACK

Authors
WINEY M
Citation
M. Winey, GENOME STABILITY - KEEPING THE CENTROSOME CYCLE ON TRACK, Current biology, 6(8), 1996, pp. 962-964
Citations number
12
Categorie Soggetti
Biology,Biology
Journal title
Current biology → ACNP
ISSN journal
09609822
Volume
6
Issue
8
Year of publication
1996
Pages
962 - 964
Database
ISI
SICI code
0960-9822(1996)6:8<962:GS-KTC>2.0.ZU;2-K
Abstract
The protein kinase Mps1 and p53 both function in centrosome duplicatio n and the spindle cell-cycle checkpoint. Defects in these functions ca n be potent sources of genomic instability by allowing mitosis to proc eed with aberrant mitotic spindles.