REGULATION OF CATHEPSIN-E EXPRESSION DURING HUMAN B-CELL DIFFERENTIATION IN-VITRO

Authors
SEALY L MOTA F RAYMENT N TATNELL P KAY J CHAIN B
Citation
L. Sealy et al., REGULATION OF CATHEPSIN-E EXPRESSION DURING HUMAN B-CELL DIFFERENTIATION IN-VITRO, European Journal of Immunology, 26(8), 1996, pp. 1838-1843
Citations number
18
Categorie Soggetti
Immunology
Journal title
European Journal of Immunology → ACNP
ISSN journal
00142980
Volume
26
Issue
8
Year of publication
1996
Pages
1838 - 1843
Database
ISI
SICI code
0014-2980(1996)26:8<1838:ROCEDH>2.0.ZU;2-I
Abstract
Cathepsin E is an aspartic proteinase which has been implicated in ant igen processing in the class II major histocompatibility complex pathw ay. In this study we show that cathepsin E, measured at both the prote in and message level, is up-regulated late in human B cell activation. The implications of this observation in terms of cathepsin E function are discussed.