L. Sealy et al., REGULATION OF CATHEPSIN-E EXPRESSION DURING HUMAN B-CELL DIFFERENTIATION IN-VITRO, European Journal of Immunology, 26(8), 1996, pp. 1838-1843
Cathepsin E is an aspartic proteinase which has been implicated in ant
igen processing in the class II major histocompatibility complex pathw
ay. In this study we show that cathepsin E, measured at both the prote
in and message level, is up-regulated late in human B cell activation.
The implications of this observation in terms of cathepsin E function
are discussed.