EXOGENOUS THYMIDINE IS PREFERENTIALLY INCORPORATED INTO HUMAN CYTOMEGALOVIRUS DNA IN INFECTED HUMAN FIBROBLASTS

Authors
MORIN J JOHANN S OHARA B GLUZMAN Y
Citation
J. Morin et al., EXOGENOUS THYMIDINE IS PREFERENTIALLY INCORPORATED INTO HUMAN CYTOMEGALOVIRUS DNA IN INFECTED HUMAN FIBROBLASTS, Journal of virology, 70(9), 1996, pp. 6402-6404
Citations number
18
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
70
Issue
9
Year of publication
1996
Pages
6402 - 6404
Database
ISI
SICI code
0022-538X(1996)70:9<6402:ETIPII>2.0.ZU;2-9
Abstract
The effect of human cytomegalovirus infection on cellular DNA synthesi s in human fibroblasts was measured by fluorometry and by incorporatio n of radiolabeled thymidine. The results show that although HCMV infec tion stimulates cellular DNA synthesis in both quiescent and serum sti mulated cells, radiolabeled thymidine is almost exclusively incorporat ed into viral DNA.