OBJECTIVES: To determine the frequency of do-not-resuscitate (DNR) ord
ers in the chronically critically ill; to identify the differences in
clinical and demographic characteristics of chronically critically ill
patients who have DNR orders and those who do not; to identify the di
fferences in the cost of care between patients with and without DNR or
ders; and to identify the differences in DNR practices between an expe
rimental special care unit and the traditional intensive care unit (IC
U). DESIGN: Randomized, prospective design with a block randomization
scheme. SUBJECTS: Two hundred twenty patients who met the following el
igibility criteria for enrollment in a parent study of the special car
e unit: an ICU stay of at least 5 days, an absence of pulmonary artery
monitoring, an absence of frequent titration of intravenous vasopress
ors, an Acute Physiology and Chronic Health Evaluation II score of les
s than 18, and a Therapeutic Intervention Scoring System score of less
than 39. SETTING: A large, urban academic medical center. MEASURES: C
linical and demographic variables describing the study populations, me
ntal status, and timing of DNR orders, mortality rates, and cost of ho
spitalization. RESULTS: There was no difference in the frequency of DN
R orders between the special care unit versus the intensive care unit-
although patients in the special care unit had a longer interval betwe
en hospital admission and initiation of the DNR order. DNR patients di
ffered from non-DNR in that they were older, less likely to be married
, and had a higher Acute Physiology and Chronic Health Evaluation II s
core on admission to the study. The mortality rate in the DNR group wa
s 71% versus 6% in the non-DNR group. There was no difference in total
costs. DNR patients were also more likely to have an impaired mental
status on admission, and more likely to have deterioration in mental s
tatus by the time of discharge than the non-DNR patients.