ORAL TUBERCULOSIS FOLLOWING AUTOLOGOUS BONE-MARROW TRANSPLANTATION FOR HODGKINS-DISEASE WITH INTERLEUKIN-2 AND ALPHA-INTERFERON IMMUNOTHERAPY

Citation
A. Toren et al., ORAL TUBERCULOSIS FOLLOWING AUTOLOGOUS BONE-MARROW TRANSPLANTATION FOR HODGKINS-DISEASE WITH INTERLEUKIN-2 AND ALPHA-INTERFERON IMMUNOTHERAPY, Bone marrow transplantation, 18(1), 1996, pp. 209-210
Citations number
17
Categorie Soggetti
Hematology,Oncology,Immunology,Transplantation
Journal title
ISSN journal
02683369
Volume
18
Issue
1
Year of publication
1996
Pages
209 - 210
Database
ISI
SICI code
0268-3369(1996)18:1<209:OTFABT>2.0.ZU;2-S
Abstract
A patient with Hodgkin's disease (HD) underwent autologous bone marrow transplantation (ABMT). Six months later while receiving interleukin (IL)-2 and alpha-interferon immunotherapy, he developed a painful lesi on in his oral cavity with a fistula in the buccal area, Excision biop sy disclosed necrotizing granulomatous inflammation with acid-fast bac illus. The patient received a 9-month course of isoniazide, rifampin a nd pyranizamide, and recovered, The possible pathophysiological mechan ism is discussed.