Intestinal malrotation is a common cause of upper gastro-intestinal ob
struction and presents with duodenal obstruction caused by volvulus of
the midgut loop. Patients are therefore at risk of catastrophic midgu
t infarction and it is a more frequent cause of duodenal obstruction i
n infants than duodenal atresia (92% in the neonatal period). Urgent u
pper contrast studies under surgical supervision are necessary in thos
e patients whose plain films are not diagnostic. Rectal bleeding is an
ominous sign, with 78% of patients having gangrenous bowel. Total mid
gut infarction is incompatible with survival in a Third-World environm
ent.