A retrospective study was undertaken to evaluate the effect of irradia
tion on 65 patients with stage I or II testicular seminomas treated at
Hillbrow Hospital with irradiation following orchidectomy. Forty-seve
n patients presented with stage I and 9 with stage II disease. AII pat
ients received infradiaphragmatic irradiation. In addition 4 patients
with stage II disease received prophylactic supradiaphragmatic irradia
tion. The 5-year overall and disease-free survival rate for all stages
and for stage I and II compared favourably with other reports in the
literature. The irradiation was well tolerated and severe long-term to
xicity was rare. Seminomas were uncommon in black patients, of whom on
ly 3 were seen in the 12-year period of this study.