OXYPHIL PARATHYROID ADENOMA ASSOCIATED WITH PRIMARY HYPERPARATHYROIDISM AND MARKED POSTOPERATIVE HUNGRY BONE SYNDROME

A fare case of functioning oxyphil parathyroid adenoma associated with primary hyperparathyroidism and marked hungry bone syndrome was revea led in a 29-year-old man with hypercalcemia and elevated circulating p arathyroid hormone (PTH) level. A large parathyroid tumor weighing 8.4 g was resected and proved to be an oxyphil adenoma. Hypocalcemia was sustained after the operation, despite intensive calcium supplementati on. During the postoperative 8 months, bone mineral density at the lum bar spine increased dramatically from 0.892 g/cm(2) to 1.244 g/cm(2), and whole body bone mineral content increased from 1,913.4 g to 2,419. 2 g. This case gives insight to the reversibility of bone loss in this disorder.