FULMINANT HEPATIC-FAILURE ASSOCIATED WITH ORAL-ADMINISTRATION OF DIAZEPAM IN 11 CATS

Authors
CENTER SA ELSTON TH ROWLAND PH ROSEN DK REITZ BL BRUNT JE RODAN I HOUSE J BANK S LYNCH LR DRING LA LEVY JK
Citation
Sa. Center et al., FULMINANT HEPATIC-FAILURE ASSOCIATED WITH ORAL-ADMINISTRATION OF DIAZEPAM IN 11 CATS, Journal of the American Veterinary Medical Association, 209(3), 1996, pp. 618
Citations number
43
Categorie Soggetti
Veterinary Sciences
Journal title
Journal of the American Veterinary Medical Association → ACNP
ISSN journal
00031488
Volume
209
Issue
3
Year of publication
1996
Database
ISI
SICI code
0003-1488(1996)209:3<618:FHAWOO>2.0.ZU;2-8
Abstract
Acute fulminant hepatic necrosis may be associated with repeated oral administration of diazepam, at recommended dosages, in cats. Initial c linical signs include lethargy, ataxia, and anorexia. If serum alanine or aspartate transaminase activity increases within 5 days of initiat ion of diazepam treatment in cats, suspending administration of the dr ug is recommended.