ZYGOTIC LETHAL MUTATIONS WITH MATERNAL EFFECT PHENOTYPES IN DROSOPHILA-MELANOGASTER .2. LOCI ON THE 2ND-CHROMOSOME AND 3RD-CHROMOSOME IDENTIFIED BY P-ELEMENT-INDUCED MUTATIONS

Screens for zygotic lethal mutations that are associated with specific maternal effect lethal phenotypes have only been conducted for the X chromosome. To identify loci on the autosomes, which represent four-fi fths of the Drosophila genome, we have used the autosomal ''FLP-DFS'' technique to screen a collection of 496 P element-induced mutations es tablished by the Berkeley Drosophila Genome Project. We have identifie d 64 new loci whose gene products are required for proper egg formatio n or normal embryonic development.