PARTIAL DELETION OF THE LONG ARM OF CHROMOSOME-5 - A FLUORESCENCE IN-SITU HYBRIDIZATION STUDY USING BAND-SPECIFIC PAINTING PROBES GENERATEDBY CHROMOSOME MICRODISSECTION

A series of 17 patients with myeloid disorders and partial deletions o f tile long arm of chromosome 5 were-investigated using fluorescence i n situ hybridization with 5q34-q35 region-specific painting probes gen erated by chromosome microdissection. This approach confirmed that par tial 5q deletions are interstitial in all the cases studied. In additi on no translocation involving chromosome 5 was detected.