ANOTHER CASE OF T(17-22)(Q22-Q13) IN AN INFANTILE DERMATOFIBROSARCOMA-PROTUBERANS

Authors
PEDEUTOUR F LACOUR JP PERRIN C HUFFERMANN K SIMON MP AYRAUD N TURCCAREL C
Citation
F. Pedeutour et al., ANOTHER CASE OF T(17-22)(Q22-Q13) IN AN INFANTILE DERMATOFIBROSARCOMA-PROTUBERANS, Cancer genetics and cytogenetics, 89(2), 1996, pp. 175-176
Citations number
6
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
89
Issue
2
Year of publication
1996
Pages
175 - 176
Database
ISI
SICI code
0165-4608(1996)89:2<175:ACOTIA>2.0.ZU;2-Q
Abstract
We have identified a new dermatofibrosarcoma protuberans (DP) case wit h a t(17;22) (q22;q13) occurring in a child. The translocation was sub stantiated by the presence of one or two copies of the sole der(22)t(1 7;22). This rearrangement added to two normal chromosomes 17 and one o r two chromosomes 22, resulted in trisomy 22cen-q13 and trisomy (or te trasomy) 17q22-25. This observation confirms the specificity of the as sociation of DP with the t(17;22) found together with extra copies of the der(22)t(17;22). It also points out a possible prevalence of trans location rather than rings in DP of the childhood disease.