Within the framework of Brueckner-Hartree-Fock method, the in-medium n
ucleon-nucleon (NN) cross section is calculated. We base our investiga
tion on a separable Paris potential for the NN interaction and a conti
nuous choice for the single particle spectrum. It is found that the in
-medium cross section is strongly modified by medium effect. In partic
ular, with increasing of nuclear density, the cross sections decrease.
This indicates a proper treatment of the density dependence of the in
-medium NN cross sections is important.