THE XENOPUS-LAEVIS HOMOLOG OF THE 64-KDA SUBUNIT OF CLEAVAGE STIMULATION FACTOR

Authors
BARBAUX S SEERY LT SCHOENBERG DR SELLAR GC WHITEHEAD AS
Citation
S. Barbaux et al., THE XENOPUS-LAEVIS HOMOLOG OF THE 64-KDA SUBUNIT OF CLEAVAGE STIMULATION FACTOR, Comparative biochemistry and physiology. B. Comparative biochemistry, 114(3), 1996, pp. 313-315
Citations number
18
Categorie Soggetti
Biology
Journal title
Comparative biochemistry and physiology. B. Comparative biochemistry → ACNP
ISSN journal
03050491
Volume
114
Issue
3
Year of publication
1996
Pages
313 - 315
Database
ISI
SICI code
0305-0491(1996)114:3<313:TXHOT6>2.0.ZU;2-2
Abstract
Cleavage stimulation factor (CstF) is composed of three subunits of 50 , 64 and 77 kDa, respectively. We report here the identification of a cDNA clone from Xenopus laevis encoding a homologue of the 64-kDa subu nit of human CstF. Comparative sequence analysis reveals that these tw o proteins are highly conserved with the exception of a unique repeat structure found in the human, but not in the X. laevis, protein. Analy sis of expression of this mRNA during X. laevis tadpole development in dicates a requirement for this protein throughout all stages of develo pment.