C. Ullmer et al., DISTRIBUTION OF 5-HT4 RECEPTOR MESSENGER-RNA IN THE RAT-BRAIN, Naunyn-Schmiedeberg's archives of pharmacology, 354(2), 1996, pp. 210-212
We have analyzed the brain distribution of the rat 5-HT4 receptor mRNA
. A receptor specific probe was used for in situ hybridization of rat
brain sections. Abundant expression of the 5-HT4 receptor mRNA was obs
erved in the olfactory system, striatum, medial habenula and the hippo
campal formation, while faint or no specific signals could be detected
in most other areas of the brain. Several brain areas which display s
trong ligand binding do not contain mRNA, suggesting an axonal localiz
ation of the 5-HT4 receptor.