In addition to metastasis, the differential diagnosis of multiple pulm
onary nodules also includes tuberculosis, sarcoidosis, and silicosis.
Rarer diseases such as amyloid tumors, rheumatic nodules and plasma-ce
ll granulomas can be the cause of this finding. This depends on the cl
inical manifestation. Based on clinical findings of lymphomatoid granu
lomatosis, the problems in diagnostics using bronchoscopy, mediastinos
copy and thoracoscopy are outlined. Etiology, morphology and different
ial diagnosis of lymphomatoid granulomatosis versus necrotizing inflam
matory or neoplastic lesions are discussed. Treatment and prognosis ar
e described.