STUDIES ON THE DIASTEREOSELECTIVE ALKYLATION OF ENOLATE DIANION OF (S)-4-CARBOETHOXYMETHYL-2-OXAZOLIDINONE

Authors
HA DC KIL KE CHOI KS PARK HS
Citation
Dc. Ha et al., STUDIES ON THE DIASTEREOSELECTIVE ALKYLATION OF ENOLATE DIANION OF (S)-4-CARBOETHOXYMETHYL-2-OXAZOLIDINONE, Tetrahedron letters, 37(32), 1996, pp. 5723-5726
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
32
Year of publication
1996
Pages
5723 - 5726
Database
ISI
SICI code
0040-4039(1996)37:32<5723:SOTDAO>2.0.ZU;2-1
Abstract
Diastereoselective alkylation of enolate dianion of (S)-4-carboethoxym ethyl-2-oxazolidinone has been studied. The increased anti-selectivity in the presence of HMPA was explained by stereoelectronic effect of t he electron-rich nitrogen atom of the oxazolidinone amidate. Copyright (C) 1996 Elsevier Science Ltd