SYNTHESIS OF HETEROCYCLES - CONSTRUCTION OF THE 1-AZABICYCLO[2.2.1]HEPTYL SYSTEM BY SEQUENTIAL RING-CLOSURE OF ACYCLIC BETA-AMMONIO SUBSTITUTED RADICALS

Authors
DELLA EW KNILL AM
Citation
Ew. Della et Am. Knill, SYNTHESIS OF HETEROCYCLES - CONSTRUCTION OF THE 1-AZABICYCLO[2.2.1]HEPTYL SYSTEM BY SEQUENTIAL RING-CLOSURE OF ACYCLIC BETA-AMMONIO SUBSTITUTED RADICALS, Tetrahedron letters, 37(32), 1996, pp. 5805-5808
Citations number
5
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
32
Year of publication
1996
Pages
5805 - 5808
Database
ISI
SICI code
0040-4039(1996)37:32<5805:SOH-CO>2.0.ZU;2-J
Abstract
Treatment of an irradiated solution of 1-(2-propynyl)-1-bis(2-phenylse lenylethyl)ammonium iodide in tert-amyl alcohol with tributyltin hydri de is found to be an effective procedure for the synthesis of 1,4-dime thyl-1-azoniabicyclo-[2.2.1]heptane iodide, Attachment of a trimethyls ilyl or phenyl substituent to the terminal carbon of the triple bond i n the alkynyl salt leads to bridgehead-substituted bicyclic heterocycl ic salts. Copyright (C) 1996 Elsevier Science Ltd