Giant cell myocarditis is a rare idiopathic inflammatory heart disease
characterized histologically by multinucleated giant cells, and clini
cally by rapid progressive heart failure, arrhythmias, or sudden death
, often within hours to days of initial symptoms. There are two previo
usly reported cases of giant cell myocarditis with idiopathic orbital
myositis. We report a similar case in a patient who also had vitiligo,
a diagnostic endomyocardial biopsy, and survival because of a cardiac
transplant. Giant cell myocarditis should be monitored for in the cou
rse of inflammatory orbital myopathy because of its life-threatening f
ulminant course.