T. Soussi, THE HUMORAL RESPONSE TO THE TUMOR-SUPPRESSOR GENE-PRODUCT P53 IN HUMAN CANCER - IMPLICATIONS FOR DIAGNOSIS AND THERAPY, Immunology today, 17(8), 1996, pp. 354-356
Mutation of the tumor-suppressor gene y53 appears to be an important t
rigger for the development of a humoral response in cancer patients. A
s discussed here, diagnosis of an alteration in p53 can be used as a m
arker of unfavorable prognosis and indicate a potential target for imm
unotherapy.