THE VOGT-KOYANAGI-HARADA SYNDROME - ASSOCIATION WITH AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE-1

We describe a young woman with primary adrenal insufficiency, hypopara thyroidism (autoimmune polyglandular syndrome type 1), Graves disease, vitiligo, and alopecia universalis. Five years after the diagnosis, s he presented with recurrent ophthalmological and neurological disorder s as features of Vogt-Koyanagi-Harada syndrome. A marked therapeutic r esponse was noted on systemic high-dose corticosteroid treatment. To t he best of our knowledge, such a spectre of autoimmune diseases has no t been reported previously.