Jp. Mugler et Jr. Brookeman, OFF-RESONANCE IMAGE ARTIFACTS IN INTERLEAVED EPI AND GRASE PULSE SEQUENCES, Magnetic resonance in medicine, 36(2), 1996, pp. 306-313
Echo-time shifting (ETS) is used in GRASE and interleaved-EPI sequence
s to improve the phase evolutions for off-resonance signal sources. Ho
wever, even with ETS the phase evolutions still exhibit discontinuitie
s. In this work, we extend previous studies of ETS by quantitatively e
valuating the magnitude and form of the image artifacts that result fr
om these phase discontinuities. The functional form of the phase evolu
tion is used to derive the general conditions under which artifacts ar
e expected. The artifacts for two sequence structures are then evaluat
ed as a function of off-resonance frequency and data sampling period b
y calculating point spread functions and simulated images. It was foun
d that even when ETS is used to improve the phase evolutions, periodic
phase discontinuities may degrade image quality by producing ghosting
artifacts of edges. These artifacts are similar to those that commonl
y occur with periodic motion. From our results recommendations are der
ived for limiting the ghosting artifacts.