Purpose: To show that intracranial tuberculosis (TB) often masquerades
as brain tumour. Material and Methods: Forty-six patients with intrac
ranial TB, who after CT at the local hospital were referred for surger
y or radiotherapy of brain tumour, are presented. Sometimes the correc
t diagnosis was first established during surgery for tumour. Results:
The differentiation between TB and gliomas, meningiomas, metastases, o
r lpmphomas may be impossible from the clinical history and CT finding
s. Angiography, done in 25 of our cases, often helped by not showing t
he expected tumour vasculature. MR, performed in 9 patients, helped by
demonstrating a layered capsule on T2-weighted images in 4 of the les
ions (hypointense rim outside hyperintense rim); the centres of the le
sions were of decreased, usually very mixed T2 signal intensity. Concl
usion: Even in patients with findings typical of brain tumour, TB rema
ins an important differential diagnosis.