It has been pediatric dogma that most children with cystic fibrosis (C
F) have pansinusitis and few are symptomatic, To reassess this premise
, we compared symptoms, clinical examinations, radiographic and surgic
al findings, and results of treatment in 19 children with cystic fibro
sis who had undergone computed tomography at St, Christopher's Hospita
l (Philadelphia) hom 1991 to 1994. We found two distinct patterns of s
inus disease: chronic sinusitis (n = 3) and polyposis (n = 12). Two of
the patients with polyposis had ethmoid mucoceles and 1 child had no
sinus disease at all, Children with chronic sinusitis had headache as
a major complaint, while those with polyposis suffered nasal obstructi
on alone unless a mucocele was present, Surgery provided marked and la
sting improvement in the 14 patients who were operated on.