S. Guadagni et al., HURTHLE CELL ADENOMA OF THE THYROID - IN 32 CONSECUTIVE CASES, Journal of the Royal College of Surgeons of Edinburgh, 41(4), 1996, pp. 246-249
Hurthle cell neoplasms of the thyroid gland are uncommon but potential
ly lethal lesions, the treatment of which is controversial because of
a lack of information about their biological and clinical behaviour. B
ased on histological criteria Hurthle cell tumours cannot always be se
parated accurately into benign and malignant. Unexpected evolutions wi
th malignant late recurrence of an adenoma previously labelled as beni
gn have been reported. The authors reviewed the clinical and pathologi
cal features of 32 patients with Hurthle cell adenomas. The results su
ggest that total thyroidectomy 'de principe' is not necessary and that
some electron microscopy criteria are useful to understand the nature
and to predict the biological deportment of Hurthle cell adenomas.