To gain a better understanding of the effects on medical schools of tr
ansformations in medical practice, science, and public expectations, t
he Association of American Medical Colleges (AAMC) constituted the Adv
isory Panel on the Mission and Organization of Medical Schools (APMOMS
) in 1994. APMOMS created six working groups to address the issues dee
med by panel members to he of highest priority. This article is a repo
rt of the findings of the Working Group on Capturing the Promise of Me
dical Research, which addressed questions concerning the direction of
research and the integration of scientific developments in medical edu
cation and practice. The working group explored a broad panorama of is
sues, including those related to sustaining the accomplishments, momen
tum, and progress of medical research. A dominant theme emerged: the c
entral importance of an environment of discovery to the core missions
of medical schools. The present article consists of the group's commen
ts and recommendations on the main topic - the promise of biomedical r
esearch in relation to medical education - and their comments and reco
mmendations on five other topics that have important relationships to
the main topic and to the group's central charge. These are ethics; ac
ademia-industry relations; the administrative structure of medical sch
ools; university-medical school relations; and research funding.