A retrospective study of 13 patients with metastases to the upper cerv
ical spine was designed to examine the clinical efficacy of surgical t
reatment. All patients had severe neck pain and two had quadriplegia.
Eleven patients underwent operative posterior stabilization, and two p
atients were treated with a brace and radiotherapy. Pain relief after
surgery was significant so that 10 of the 11 patients could leave bed
and resume their normal activities. The other two patients who were tr
eated nonoperatively had severe dementia and sudden death from a respi
ratory arrest after a fall, despite temporary relief from pain. Surger
y may be very successful in improving the quality of life of patients
who have pain and/or paralysis caused by metastases to the upper cervi
cal spine.