Myelopathy due to calcium pyrophosphate dihydrate (CPPD) crystals in t
he cervical spine is rare. Neuropathic-like joints are also uncommon m
anifestations of CPPD crystal disease. We describe a 79-year-old woman
with multiple neuropathic joints containing CPPD crystals. She also h
ad a large mass containing CPPD crystals impinging on the cervical spi
nal cord, causing a myelopathy. She appears to be the first patient wi
th this combination of unusual clinical features with CPPD disease.