Y. Mimaki et al., STEROIDAL SAPONINS FROM NOLINA-RECURVATA STEMS AND THEIR INHIBITORY ACTIVITY ON CYCLIC-AMP PHOSPHODIESTERASE, Phytochemistry, 42(6), 1996, pp. 1609-1615
Seven steroidal saponins were isolated from the stems of Nolina recurv
ata, five of which appeared to be new compounds and were assigned as s
pirosta-5,25(27)-diene-1 beta,3 beta-diol (neoruscogenin) xylopyranosy
l-(1-->3)]-alpha-L-arabinopyranoside}, (25S)-spirost-5-ene-1 beta,3 be
ta-diol [(25S)-ruscogenin] xylopyranosyl-(1-->3)]-alpha-l-arabinopyran
oside}, neoruscogenin rhamnopyranosyl-(1-->2)-O-[beta-D-xylopyranosyl-
(1 -->3)]-beta-D-fucopyranoside}, glucopyranosyl-22-O-methylfurosta-5,
25(27)-diene-1 beta,3 beta,22 xi,26-tetrol -xylopyranosyl-(1-->3)]-alp
ha-L-arabinopyranoside} and a-D-glucopyranosylfurosta-5,20(22),25(27)-
triene-1 beta,3 beta,26-triol hamnopyranosyl-(1-->2)-alpha-L-arabinopy
ranoside}. The isolated saponins were evaluated for their inhibitory a
ctivity on cyclic AMP phosphodiesterase to identify new compounds with
medicinal potential.