CARBOXYLATED ALPHA-PYRONE DERIVATIVES AND FLAVONOIDS FROM THE LIVERWORT DUMORTIERA-HIRSUTA

Three new carboxylated cu-pyrone derivatives, dumortins A-C, and a new flavone glycoside have been isolated from the liverwort, Dumortiera h irsuta, together with the known flavonoids, luteolin, luteolin-5-O-bet a-D-glucuronide and luteolin-7-O-beta-D-glucuronide. The structures of the new alpha-pyrones were confirmed spectroscopically as ,4'-dihydro xyphenyl)-ethyl]-6-carboxy-alpha-pyrone and 4'-dihydroxyphenyl)-ethyl] -6-carboxy-alpha-pyrone. The new flavonoid was elucidated as luteolin- 5-O-beta-D-glucuronide-6 ''-methyl ester. The structures of dumortins A and B were confirmed by independent chemical synthesis. Copyright (C ) 1996 Elsevier Science Ltd